<strong>Antibacterial activity of strawberry fruit extract against <em>Streptococcus sanguinis</em> (ATCC 10556)</strong>

Introduction: Streptococcus sanguinis is a facultative anaerobic Gram-positive bacteria known as pioneer that plays role in creating the biofilm oral cavity. Strawberry fruit (Fragaria x ananassa) an edible widely used for study their active compound synergy to improve health. This aims analyse antibacterial activity of strawberry against S. (ATCC 10556). Methods: An explorative was conducted with high concentration methanol extract from fruit. Antibacterial tested on extract; afterwards, fractionated and divided into three fractions: water, ethyl acetate, hexane. Zone inhibition assess most effective fraction among those three, then continued by testing Minimum Inhibitory Concentration (MIC) Bactericidal (MBC). Results: zone acetate 1%, 2%, 3% ,4% 5% sequentially were 7.3 mm,10.2 mm, 12.3 16.3 mm 16.1 mm. Ethyl 4% create size compared others. The value 0.25%. It obtained diluting microplate. (MBC) 2%. Conclusion: had inhibitory 4%, MIC 0.25%, MBC